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Health Tips:
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CONTINUED...
by
Mitra Ray, Ph.D.
[Excerpted from From Here to Longevity, Chapter Eight]
Antioxidant Status of Humans: A Balancing Act
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Antioxidant Sources
- Genetic factors
- Diet rich in antioxidants
- Moderate exercise
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Free Radical Production
- Normal metabolism
- Genetic factors
- Junk food
- Overeating
- Environmental toxins
- Alcohol
- Injury and trauma
- Disease
- Medications and treatments
- Strenuous exercise
- Physiological and emotional stress
- Smoking
- Overexposure to sunlight
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Whenever we burn fuel of any kind, we produce toxins. Think about a
wood fire in your fireplace, or the gas combustion engine in your car.
Burning or combustion requires oxygen; therefore this chemical process is
also known as oxidation. In much the same way, our cells need to “burn”
metabolites for energy. During metabolism free radicals are produced as a
by-product. A free radical is a highly unstable molecule that is
aggressively searching for its missing electron. Free radicals can also be
purposefully generated within the body for such processes as:
- phagocytosis: immune cells called macrophages fight infection by
surrounding and consuming debris and foreign bodies with the use of free
radicals
- signal transduction: cells perceive input and carry out necessary
functions based on that input using free radicals as messenger
molecules.
In these processes, the free radical production is highly regulated and
their awesome chemical power is being put to use to serve the body. What
we need to focus our attention on, however, is the unregulated
overproduction of free radicals. In this case, free radicals become loaded
guns looking for a target, ready to harm any innocent molecule in the body
that they come into contact with.
This list of what are considered to be essential nutrients is far too
short and sadly outdated in my opinion. The bottom line is that Mother
Nature’s foods contain a multitude of important nutrients; as science and
technology progress, we learn more and more about them, give them names,
try to categorize them, and study their specific roles in our health.
Still we must recognize that our knowledge is incomplete about what is
truly essential and what is not.
The important molecules that were discovered in the “first round” of
studying food were given the name “vitamins.” These vitamins act as
important cofactors for making enzymatic reactions work in the body. As we
discovered the role of free radicals, we found that some of these vitamins
also acted as antioxidants to protect the body from free radical damage. A
preponderance of free radicals leaves a trail of damaged molecules in the
body. Then the body has the burden of working hard to clean up the damaged
molecules, and producing new functioning molecules to replace the damaged
ones, or even worse, replacing entire cells. This process exacts a huge,
unnecessary toll from the body; we call it oxidative stress. No wonder we
feel tired all the time! We do have a limited, inborn capacity to defend
against free radicals; however, it is crucial to realize that the scale is
always tilted in their favor. The balance between free radical activity
and antioxidants is often referred to as the antioxidant status in humans.
In time we began to discover that there were actually many antioxidants to
be found in food. Today, as science progresses further, we are finding
other nutrients in food, and their roles are still being determined. While
there is much more that remains unknown than known, it’s clear that we
need to pay close attention to the power of Mother Nature’s foods in
keeping the body functioning optimally. For instance, most of the
antioxidants found in fruits and vegetables still haven’t been identified
and recognized officially as essential; yet the body cannot manufacture
most of the antioxidants it needs in order to protect itself from
oxidative stress.
The various colors of produce represent different families of
antioxidants: such as the orange carotenes found in carrots, the purple
anthocyanins found in berries, or the red lycopenes found in tomatoes. In
order to thrive, we do know that the body requires the full color spectrum
of antioxidants, just as it requires all of the nine essential amino
acids. Yet, our diet is often tragically lacking in these vibrant and
protective plant pigments. We all need to have the power of antioxidants
on our side when it comes to confronting oxidative stress.
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Susan Silberstein, Ph.D., is the Executive Director of the Center for Advancement in
Cancer Education [CACE], a national non-profit organization she
founded in 1977.
Richard E. DuBois, M.D., is one of the world’s leading
authorities on infectious diseases.
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